Institute of Molecular Biomedicine

IMBM is a research institute of the Faculty of Medicine at the Comenius University in Slovakia. We are located in Bratislava, both in the heart of the capital’s old town at Sasinkova 4, and in the Biomedical research center of the Slovak Academy of Sciences at Dubravská street 9.  The mission of IMBM is simple: to do (and enjoy doing) science. As of our staff, we have a vast range of educational background – from molecular biology, biophysics, biotechnology or physiology, up to medicine. While we believe that interdisciplinarity is a key scientific value. Furthermore, our partnerships extend to collaborating with clinicians and complementary research institutes all around the globe (Aachen, Gothenburg, New York, Boston, Hradec Králové…). This is a great enrichment to our  esearch. Of course, our institute is also home for many PhD students that are trained here in experimental and laboratory medicine, as well as undergraduate and graduate students that work on their bachelor/master/doctoral thesis with us. Moreover, our teaching takes place at the Faculty of Medicine and the Faculty of Natural  Sciences of the Comenius University. Ultimately, IMBM is an institute of open-minded people, scientists, who share their devotion to science. If you share this devotion with us, apply and come join us at the Institute of Molecular Biomedicine in Bratislava.

 

News

New research: Deoxyribonuclease and its effect on rheumatoid arthritis

We warmly congratulate several of our colleagues who recently published an article examining the effect of the therapeutic agent – deoxyribonuclease (DNase) on an animal model of collagen antibody-induced arthritis. The results suggest that exogenously administered DNase does not prevent the development of inflammation in this model. You can find the whole publication here.

October 15, 2024

World Sepsis Day

Thus, a month ago, September 13, was World Sepsis Day. The BEATsepsis Consortium has organized several events to raise awareness of sepsis and discuss research bridging the gap between bench and bedside. On World Sepsis Day, the research group of Dr Ján Frič at the Faculty Hospital of St. Anny organized a workshop in Brno to exchange the latest knowledge, including our colleagues actively participating in this project.

October 13, 2024

IMBM again among the finalists of Falling Walls Lab Slovakia

We were once again well-represented in the Falling Walls Lab Slovakia 2024 finals. Three of our PhD students presented their innovative ideas to the expert committee. Alena Potočárová presented an idea with the support of data from the use of human DNA monitoring in wastewater, Kristína Lichá focused on extracellular vesicles as carriers of mitochondrial DNA in biomedicine, and Emil Bečka presented a different perspective on solving the infection of trauma patients.

October 9, 2024

Science

Projects

  • KEGA: KEGA 071UK-4/2022 Innovation of Practical Biomedical Research Courses for Doctoral Students
  • APVV: APVV-20-0472 Rapid identification of pathogens in sepsis patients using third-generation nanopore real-time sequencing
  • APVV: APVV-22-0554 Deoxyribonuclease 1l3 in the biology of extracellular DNA

Published papers

  • Oxidative Stress Markers and Na,K-ATPase Enzyme Kinetics Are Altered in the Cerebellum of Zucker Diabetic Fatty fa/fa Rats: A Comparison with Lean fa/+ and Wistar Rats
  • Shank3 deficiency alters midbrain GABAergic neuron morphology, GABAergic markers and synaptic activity in primary striatal neurons
  • Assessing sociability using the Three-Chamber Social Interaction Test and the Reciprocal Interaction Test in a genetic mouse model of ASD